| Zone | Vessels | Finding | Significance |
|---|---|---|---|
| Aorta / Iliac | Abdominal aorta, common iliacs | Relatively clean — patent lumen, no aneurysm, no gross calcification | Favorable |
| Thighs (NEW) | Bilateral SFAs (Superficial Femoral Arteries) | Moderate-to-severe circumferential Mönckeberg calcification — bilateral, symmetric ring pattern | New finding |
| Lower legs (known) | Tibial, peroneal arteries | Severe calcification — consistent with prior Doppler findings | Previously documented |
| Medication | Purpose | Next Step |
|---|---|---|
| Ezetimibe (Zetia) 10mg | Lowers LDL additional 15–20% on top of statin | Raise with cardiologist if Aug LDL >55 |
| PCSK9 inhibitor (Repatha/Praluent/Leqvio) | Lowers LDL additional 50–60%; injectable | Qualifies for prior auth (T1D + PAD); discuss if LDL still >55 |
| Aspirin 81mg + Rivaroxaban 2.5mg BID | COMPASS trial: reduces major adverse limb events in PAD | Raise with vascular surgeon — aspirin reaction needs clarification first |
| ACE inhibitor (Ramipril) | HOPE trial: reduces CV events in PAD even without hypertension | Raise with cardiologist; eGFR check required first |
| SGLT2 inhibitor (empagliflozin/dapagliflozin) | CV + renal protection; off-label T1D use | Raise with endocrinologist and cardiologist |
| Vitamin K2 (MK-7) 100–200mcg/day | Activates Matrix Gla Protein — inhibits vascular calcification (Mönckeberg-specific) | OTC supplement; mechanistically sound; not guideline-backed |
| Magnesium glycinate 200–400mg/day | Inverse association with vascular calcification; BP + insulin sensitivity | OTC supplement; discuss with physician |
| Specialist | Role | Status |
|---|---|---|
| Dr. Gordon UCLA Cardiology DTLA · 213-988-8380 700 W. 7th St, Suite S270, Los Angeles CA 90017 |
Cardiologist — coronary screening, arrhythmia workup, lipid optimization | Aug 26 appt |
| Dr. Anand Gautam, MD Vascular Surgery · Inglewood · 310-673-6950 575 E. Hardy St, Suite 322, Inglewood CA 90301 |
Vascular surgeon — PAD, CTA interpretation, revascularization planning | Aug 17 TODAY |
| Endocrinologist (T1D-focused) | CGM/insulin optimization, SGLT2 evaluation, A1c management | Not yet engaged — NEEDED |
| Podiatrist | T1D + PAD foot risk — quarterly minimum, wound surveillance | Not established — NEEDED |
| Nephrologist | eGFR baseline after 23y T1D + post-contrast CT; pre-ACE inhibitor check | Consider consult |
| Marker | Target | Last Value | Status |
|---|---|---|---|
| LDL (Low-Density Lipoprotein) | <55 mg/dL — AHA/ACC 2018 very high risk (T1D + PAD) | 114 mg/dL (May 2026) | 🔴 Above target |
| HDL (High-Density Lipoprotein) | >40 mg/dL | 51 mg/dL (May 2026) | ✅ OK |
| Triglycerides | <150 mg/dL | 73 mg/dL (May 2026) | ✅ OK |
| HbA1c | Per endocrinologist / track TIR >70% | 9.3% (May 2026) — Aug pending | 🔴 High (improving) |
| TIR (Time in Range) | >70% (blood glucose 70–180 mg/dL) | 22% May → 55% Aug 2–8 | ⚠️ Improving ↑↑ |
| eGFR (estimated Glomerular Filtration Rate) | Baseline needed | Not on file | ⏳ ORDER ASAP |
| Blood Pressure | <130/80 mmHg | Monitor | Monitor |
| TBI (Toe-Brachial Index) | >0.6 normal · <0.25 = critical | Pending (use TBI not ABI — Mönckeberg makes ABI falsely high) | Pending |